The Sacklers are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Keefe begins with the three doctor brothers, Raymond, Mortimer and Arthur, who weathered the poverty of the Great Depression and...