Jack and Annie are transported by their magic tree house to the time of the Civil War where they meet Clara Barton.

Profiles ten women from different times and fields of endeavor whose lives are meant to serve as role models, including Pocahontas, Harriet Tubman, Elizabeth Cady Stanton, Susan B. Anthony, Clara Barton, Emily Dickinson, Mary Cassatt, Helen Keller, Eleanor Roosevelt, Amelia Earhart, and Margaret Mead.